Railey valeroso biography of williams
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Published in final edited form as: Genesis. 2016 Oct 31;54(11):593–601. doi: 10.1002/dvg.22985
Abstract
The Neurokinin 1 Receptor (NK1R), which binds Substance P, is expressed in discrete populations of neurons throughout the nervous system, where it has numerous roles including the modulation of pain and affective behaviors. Here, we report the generation of a NK1R-CreER knockin allele, in which CreERT2 replaces the coding sequence of the TACR1 gene (encoding NK1R) in order to gain genetic access to these cells. We find that the NK1R-CreER allele mediates recombination in many regions of the nervous system that are important in pain and anxiety including the amygdala, hypothalamus, frontal cortex, raphe nucleus, and dorsal horn of the spinal cord. Other cell types that are labeled by this allele include amacrine cells in the retina and fibroblasts in the skin. Thus, the NK1R-CreER mouse line is a valuable new tool fo
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Full Cast & Crew
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Click (Philippine TV series)
Philippine television drama series
| Click | |
|---|---|
Title card in 2002 | |
| Genre | Drama |
| Developed by | Don Michael Perez |
| Written by |
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| Directed by | Mac Alejandre |
| Theme music composer | Jingle Buena |
| Opening theme |
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| Country of origin | Philippines |
| Original language | Tagalog |
| No. of seasons | 5 |
| No. of episodes | 248 |
| Executive producers |
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| Producers | |
| Production locations | Metro Manila, Philippines |
| Cinematography | Jay Linao |
| Camera setup | Multiple-camera setup |
| Running time | 27–88 minutes |
| Production company | GMA Entertainment TV |
| Network | GMA Network |
| Release | December 4, 1999 (1999-12-04) – July 24, 2004 (2004-07-24) |