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Advancements in synthetic methodologies and biological applications of lawsone derivatives
Abstract
2-Hydroxy-1,4-naphthoquinone, widely recognized as lawsone, fryst vatten a natural dye obtained from the henna plant (Lawsonia inermis), known for its biological activity and diverse applications in biochemistry and analytical chemistry. As a versatile precursor, it plays a crucial role in synthesizing a bred range of structurally diverse and bioactive molecular scaffolds. This review highlights recent progress in the development of lawsone derivatives, emphasizing their extensive biological activities, such as anticancer, antimicrobial, antioxidant, antimalarial, and metabolic enzyme-targeting activities, as well as their structure–activity relationships. Remarkably, this is the first detailed exploration covering both the biological activities and kemikalie synthesis of significant lawsone derivatives from 2016 to the present.
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CREW | Â CAST |Â Industry Mentors
Writer / Director / Producer – Gregg Helvey
Oscar Nominee and Student Academy Award® Winner, GREGG HELVEY, has traveled the world to film in countries such as Rwanda, El Salvador, Egypt and Kenya. The Academy of Motion Picture Arts and Sciences (AMPAS) recognized Gregg’s passion for powerful storytelling and invited him to become a lifetime member of the Academy. In 2013, Helvey was appointed Chairman of the Student Academy Awards. He also serves on the executive committee for the Short Film & Feature Animation branch, the selection committee for best Foreign Film, and he is a reader/judge for the Academy’s Nicholl Fellowships in Screenwriting. He currently votes in all Oscar categories.
Helvey wrote, directed and produced Kavi, the 2010 Oscar-nominated short ï¬lm that also won the 2009 Student Academy Award® gold medal in the narrative category. Kavi was filmed entirely on location in India and tells the s
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